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Mind the Gap—Deciphering GPCR Pharmacology Using 3D Pharmacophores and Artificial Intelligence

G protein-coupled receptors (GPCRs) are amongst the most pharmaceutically relevant and well-studied protein targets, yet unanswered questions in the field leave significant gaps in our understanding of their nuanced structure and function. Three-dimensional pharmacophore models are powerful computat...

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Detalles Bibliográficos
Autores principales:	Noonan, Theresa, Denzinger, Katrin, Talagayev, Valerij, Chen, Yu, Puls, Kristina, Wolf, Clemens Alexander, Liu, Sijie, Nguyen, Trung Ngoc, Wolber, Gerhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695541/ https://www.ncbi.nlm.nih.gov/pubmed/36355476 http://dx.doi.org/10.3390/ph15111304

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