Phenotypic Evaluation of Nucleoside Analogues against Trypanosoma cruzi Infection: In Vitro and In Vivo Approaches

Chagas disease, caused by Trypanosoma cruzi (T. cruzi), is a serious public health problem. Current treatment is restricted to two drugs, benznidazole and nifurtimox, displaying serious efficacy and safety drawbacks. Nucleoside analogues represent a promising alternative as protozoans do not biosynt...

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Detalles Bibliográficos
Autores principales: Fiuza, Ludmila F. de A., Batista, Denise G. J., Girão, Roberson D., Hulpia, Fabian, Finamore-Araújo, Paula, Aldfer, Mustafa M., Elmahallawy, Ehab Kotb, De Koning, Harry P., Moreira, Otacílio, Van Calenbergh, Serge, Soeiro, Maria de Nazaré C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695592/
https://www.ncbi.nlm.nih.gov/pubmed/36432189
http://dx.doi.org/10.3390/molecules27228087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695592/
https://www.ncbi.nlm.nih.gov/pubmed/36432189
http://dx.doi.org/10.3390/molecules27228087

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