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In Vivo Preclinical Assessment of β-Amyloid–Affine [(11)C]C-PIB Accumulation in Aluminium-Induced Alzheimer’s Disease-Resembling Hypercholesterinaemic Rat Model

Aluminum (Al) excess and hypercholesterinaemia are established risks of Alzheimer’s disease (AD). The aim of this study was to establish an AD-resembling hypercholesterinaemic animal model—with the involvement of 8 week and 48 week-old Fischer-344 rats—by Al administration for the safe and rapid ver...

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Detalles Bibliográficos
Autores principales: Képes, Zita, Barkóczi, Alexandra, Szabó, Judit P., Kálmán-Szabó, Ibolya, Arató, Viktória, Jószai, István, Deák, Ádám, Kertész, István, Hajdu, István, Trencsényi, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695619/
https://www.ncbi.nlm.nih.gov/pubmed/36430429
http://dx.doi.org/10.3390/ijms232213950