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In Vivo Preclinical Assessment of β-Amyloid–Affine [(11)C]C-PIB Accumulation in Aluminium-Induced Alzheimer’s Disease-Resembling Hypercholesterinaemic Rat Model
Aluminum (Al) excess and hypercholesterinaemia are established risks of Alzheimer’s disease (AD). The aim of this study was to establish an AD-resembling hypercholesterinaemic animal model—with the involvement of 8 week and 48 week-old Fischer-344 rats—by Al administration for the safe and rapid ver...
Autores principales: | Képes, Zita, Barkóczi, Alexandra, Szabó, Judit P., Kálmán-Szabó, Ibolya, Arató, Viktória, Jószai, István, Deák, Ádám, Kertész, István, Hajdu, István, Trencsényi, György |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695619/ https://www.ncbi.nlm.nih.gov/pubmed/36430429 http://dx.doi.org/10.3390/ijms232213950 |
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