Conservation of Importin α Function in Apicomplexans: Ivermectin and GW5074 Target Plasmodium falciparum Importin α and Inhibit Parasite Growth in Culture

Signal-dependent transport into and out of the nucleus mediated by members of the importin (IMP) superfamily of nuclear transporters is critical to the eukaryotic function and a point of therapeutic intervention with the potential to limit disease progression and pathogenic outcomes. Although the ap...

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Detalles Bibliográficos
Autores principales: Walunj, Sujata B., Wang, Chunxiao, Wagstaff, Kylie M., Patankar, Swati, Jans, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695642/
https://www.ncbi.nlm.nih.gov/pubmed/36430384
http://dx.doi.org/10.3390/ijms232213899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695642/
https://www.ncbi.nlm.nih.gov/pubmed/36430384
http://dx.doi.org/10.3390/ijms232213899

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