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Selection of an Aptamer against the Enzyme 1-deoxy-D-xylulose-5-phosphate Reductoisomerase from Plasmodium falciparum

The methyl erythritol phosphate (MEP) pathway of isoprenoid biosynthesis is essential for malaria parasites and also for several human pathogenic bacteria, thus representing an interesting target for future antimalarials and antibiotics and for diagnostic strategies. We have developed a DNA aptamer...

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Detalles Bibliográficos
Autores principales: Roca, Carlota, Avalos-Padilla, Yunuen, Prieto-Simón, Beatriz, Iglesias, Valentín, Ramírez, Miriam, Imperial, Santiago, Fernàndez-Busquets, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695703/
https://www.ncbi.nlm.nih.gov/pubmed/36432706
http://dx.doi.org/10.3390/pharmaceutics14112515