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Selection of an Aptamer against the Enzyme 1-deoxy-D-xylulose-5-phosphate Reductoisomerase from Plasmodium falciparum
The methyl erythritol phosphate (MEP) pathway of isoprenoid biosynthesis is essential for malaria parasites and also for several human pathogenic bacteria, thus representing an interesting target for future antimalarials and antibiotics and for diagnostic strategies. We have developed a DNA aptamer...
Autores principales: | Roca, Carlota, Avalos-Padilla, Yunuen, Prieto-Simón, Beatriz, Iglesias, Valentín, Ramírez, Miriam, Imperial, Santiago, Fernàndez-Busquets, Xavier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695703/ https://www.ncbi.nlm.nih.gov/pubmed/36432706 http://dx.doi.org/10.3390/pharmaceutics14112515 |
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