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Sargachromenol Isolated from Sargassum horneri Attenuates Glutamate-Induced Neuronal Cell Death and Oxidative Stress through Inhibition of MAPK/NF-κB and Activation of Nrf2/HO-1 Signaling Pathway

Oxidative stress-induced neuronal cell loss is considered to be the major mechanism underlying the pathogenesis of neurodegenerative diseases, which could be induced by a high concentration of glutamate. In this study, sargachromenol (SC) was isolated from a marine brown seaweed Sargassum horneri (S...

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Detalles Bibliográficos
Autores principales: Han, Eui-Jeong, Zhang, Chunying, Kim, Hyun-Soo, Kim, Ji-Yul, Park, Sang-Muyn, Jung, Won-Kyo, Ahn, Ginnae, Cha, Seon-Heui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695719/
https://www.ncbi.nlm.nih.gov/pubmed/36421988
http://dx.doi.org/10.3390/md20110710