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Plasma p‐tau181/Aβ(1‐42) ratio predicts Aβ‐PET status and correlates with CSF‐p‐tau181/Aβ(1‐42) and future cognitive decline
BACKGROUND: In Alzheimer's disease (AD), plasma amyloid beta (Aβ)(1‐42) and phosphorylated tau (p‐tau) predict high amyloid status from Aβ positron emission tomography (PET); however, the extent to which combination of these plasma assays can predict remains unknown. METHODS: Prototype Simoa as...
Autores principales: | Fowler, Christopher J., Stoops, Erik, Rainey‐Smith, Stephanie R., Vanmechelen, Eugeen, Vanbrabant, Jeroen, Dewit, Nele, Mauroo, Kimberley, Maruff, Paul, Rowe, Christopher C., Fripp, Jurgen, Li, Qiao‐Xin, Bourgeat, Pierrick, Collins, Steven J., Martins, Ralph N., Masters, Colin L., Doecke, James D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695763/ https://www.ncbi.nlm.nih.gov/pubmed/36447478 http://dx.doi.org/10.1002/dad2.12375 |
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