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High Instantaneous Inhibitory Potential of Bictegravir and the New Spiro-β-Lactam BSS-730A for HIV-2 Isolates from RAL-Naïve and RAL-Failing Patients

Integrase inhibitors (INIs) are an important class of drugs for treating HIV-2 infection, given the limited number of drugs active against this virus. While the clinical efficacy of raltegravir and dolutegravir is well established, the clinical efficacy of bictegravir for treating HIV-2 infected pat...

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Detalles Bibliográficos
Autores principales: Bártolo, Inês, Moranguinho, Inês, Gonçalves, Paloma, Diniz, Ana Rita, Borrego, Pedro, Martin, Francisco, Figueiredo, Inês, Gomes, Perpétua, Gonçalves, Fátima, Alves, Américo J. S., Alves, Nuno, Caixas, Umbelina, Pinto, Inês V., Barahona, Isabel, Pinho e Melo, Teresa M. V. D., Taveira, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695772/
https://www.ncbi.nlm.nih.gov/pubmed/36430777
http://dx.doi.org/10.3390/ijms232214300