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Effect of Natural Adenylcyclase/cAMP/CREB Signalling Activator Forskolin against Intra-Striatal 6-OHDA-Lesioned Parkinson’s Rats: Preventing Mitochondrial, Motor and Histopathological Defects

Parkinson’s disease (PD) is characterised by dopaminergic neuronal loss in the brain area. PD is a complex disease that deteriorates patients’ motor and non-motor functions. In experimental animals, the neurotoxin 6-OHDA induces neuropathological, behavioural, neurochemical and mitochondrial abnorma...

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Detalles Bibliográficos
Autores principales: Alharbi, Metab, Alshammari, Abdulrahman, Kaur, Gurpreet, Kalra, Sanjeev, Mehan, Sidharth, Suri, Manisha, Chhabra, Swesha, Kumar, Nitish, Alanazi, Wael A., Alshanwani, Aliah R., AL-Ghamdi, Abdullah Hamed, Narula, Acharan S., Kalfin, Reni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695774/
https://www.ncbi.nlm.nih.gov/pubmed/36432051
http://dx.doi.org/10.3390/molecules27227951