Granulosa Cell Specific Loss of Adar in Mice Delays Ovulation, Oocyte Maturation and Leads to Infertility

Adenosine deaminases acting on RNA-(ADAR) comprise one family of RNA editing enzymes that specifically catalyze adenosine to inosine (A-to-I) editing. A granulosa cell (GC) specific Adar depleted mouse model [Adar (flox/flox):Cyp19a1-Cre/+ (gcAdarKO)] was used to evaluate the role of ADAR1 during th...

Descripción completa

Detalles Bibliográficos
Autores principales: Nelson, Rikki N., Chakravarthi, V. Praveen, Ratri, Anamika, Hong, Xiaoman, Gossen, Jan A., Christenson, Lane K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695778/
https://www.ncbi.nlm.nih.gov/pubmed/36430478
http://dx.doi.org/10.3390/ijms232214001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695778/
https://www.ncbi.nlm.nih.gov/pubmed/36430478
http://dx.doi.org/10.3390/ijms232214001

Ejemplares similares