Subcutaneous Immunization with Unaltered Axenic Malaria Parasite Liver Stages Induces Sterile Protection against Infectious Sporozoite Challenge

Host cell-free, axenic development of liver stages (LS) of the malaria parasite has been demonstrated. Here we explored axenic liver stages as a novel live whole parasite malaria vaccine platform, which is unaltered and not prone to human-error, compared to the immunization with live-attenuated spor...

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Detalles Bibliográficos
Autores principales: Kamil, Mohd, Deveci, Gozde, Kina, Umit Y., Kappe, Stefan H. I., Aly, Ahmed S. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695791/
https://www.ncbi.nlm.nih.gov/pubmed/36366392
http://dx.doi.org/10.3390/vaccines10111884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695791/
https://www.ncbi.nlm.nih.gov/pubmed/36366392
http://dx.doi.org/10.3390/vaccines10111884

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