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Subcutaneous Immunization with Unaltered Axenic Malaria Parasite Liver Stages Induces Sterile Protection against Infectious Sporozoite Challenge
Host cell-free, axenic development of liver stages (LS) of the malaria parasite has been demonstrated. Here we explored axenic liver stages as a novel live whole parasite malaria vaccine platform, which is unaltered and not prone to human-error, compared to the immunization with live-attenuated spor...
Autores principales: | Kamil, Mohd, Deveci, Gozde, Kina, Umit Y., Kappe, Stefan H. I., Aly, Ahmed S. I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695791/ https://www.ncbi.nlm.nih.gov/pubmed/36366392 http://dx.doi.org/10.3390/vaccines10111884 |
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