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Drug Physicochemical Properties and Capsule Fill Determine Extent of Premature Gastric Release from Enteric Capsules

Intrinsically, enteric capsule shells offer several advantages compared to coating of dosage forms with enteric polymers. We undertook a systematic investigation to elucidate capsule-fill parameters that may result in premature gastric drug release from Vcaps(®) Enteric capsules (Lonza CHI, Morristo...

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Detalles Bibliográficos
Autores principales: Moghrabi, Fouad S., Fadda, Hala M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695824/
https://www.ncbi.nlm.nih.gov/pubmed/36432696
http://dx.doi.org/10.3390/pharmaceutics14112505