Spontaneous Transformation of a p53 and Rb-Defective Human Fallopian Tube Epithelial Cell Line after Long Passage with Features of High-Grade Serous Carcinoma

Ovarian cancer is one of the most lethal gynecological cancers, and 80% are high-grade serous carcinomas (HGSOC). Despite advances in chemotherapy and the development of targeted therapies, the survival rate of HGSOC has only moderately improved. Therefore, a cell model that reflects the pathogenesi...

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Detalles Bibliográficos
Autores principales: Chang, Yu-Hsun, Chu, Tang-Yuan, Ding, Dah-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695839/
https://www.ncbi.nlm.nih.gov/pubmed/36430324
http://dx.doi.org/10.3390/ijms232213843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695839/
https://www.ncbi.nlm.nih.gov/pubmed/36430324
http://dx.doi.org/10.3390/ijms232213843

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