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Potent Activation of Human but Not Mouse TRPA1 by JT010
Transient receptor potential (TRP) ankyrin repeat 1 (TRPA1), which is involved in inflammatory pain sensation, is activated by endogenous factors, such as intracellular Zn(2+) and hydrogen peroxide, and by irritant chemical compounds. The synthetic compound JT010 potently and selectively activates h...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695908/ https://www.ncbi.nlm.nih.gov/pubmed/36430781 http://dx.doi.org/10.3390/ijms232214297 |