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Potent Activation of Human but Not Mouse TRPA1 by JT010

Transient receptor potential (TRP) ankyrin repeat 1 (TRPA1), which is involved in inflammatory pain sensation, is activated by endogenous factors, such as intracellular Zn(2+) and hydrogen peroxide, and by irritant chemical compounds. The synthetic compound JT010 potently and selectively activates h...

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Detalles Bibliográficos
Autores principales:	Matsubara, Masaki, Muraki, Yukiko, Hatano, Noriyuki, Suzuki, Hiroka, Muraki, Katsuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695908/ https://www.ncbi.nlm.nih.gov/pubmed/36430781 http://dx.doi.org/10.3390/ijms232214297

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