Gallic Acid–Triethylene Glycol Aptadendrimers Synthesis, Biophysical Characterization and Cellular Evaluation

Herein, we describe the synthesis of an aptadendrimer by covalent bioconjugation of a gallic acid–triethylene glycol (GATG) dendrimer with the G-quadruplex (G4) AT11 aptamer (a modified version of AS1411) at the surface. We evaluated the loading and interaction of an acridine orange ligand, termed C...

Descripción completa

Detalles Bibliográficos
Autores principales: Miranda, André, Lopez-Blanco, Roi, Lopes-Nunes, Jéssica, Melo, Ana M., Campello, Maria Paula Cabral, Paulo, António, Oliveira, Maria Cristina, Mergny, Jean-Louis, Oliveira, Paula A., Fernandez-Megia, Eduardo, Cruz, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696068/
https://www.ncbi.nlm.nih.gov/pubmed/36432647
http://dx.doi.org/10.3390/pharmaceutics14112456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696068/
https://www.ncbi.nlm.nih.gov/pubmed/36432647
http://dx.doi.org/10.3390/pharmaceutics14112456

Ejemplares similares