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Gallic Acid–Triethylene Glycol Aptadendrimers Synthesis, Biophysical Characterization and Cellular Evaluation
Herein, we describe the synthesis of an aptadendrimer by covalent bioconjugation of a gallic acid–triethylene glycol (GATG) dendrimer with the G-quadruplex (G4) AT11 aptamer (a modified version of AS1411) at the surface. We evaluated the loading and interaction of an acridine orange ligand, termed C...
Autores principales: | Miranda, André, Lopez-Blanco, Roi, Lopes-Nunes, Jéssica, Melo, Ana M., Campello, Maria Paula Cabral, Paulo, António, Oliveira, Maria Cristina, Mergny, Jean-Louis, Oliveira, Paula A., Fernandez-Megia, Eduardo, Cruz, Carla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696068/ https://www.ncbi.nlm.nih.gov/pubmed/36432647 http://dx.doi.org/10.3390/pharmaceutics14112456 |
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