Fully Symmetric Cyclodextrin Polycarboxylates: How to Determine Reliable Protonation Constants from NMR Titration Data

Acid-base properties of cyclodextrins (CDs), persubstituted at C-6 by 3-mercaptopropionic acid, sualphadex (Suα-CD), subetadex (Suβ-CD) and sugammadex (Suγ-CD, the antidote of neuromuscular blocking steroids) were studied by (1)H NMR-pH titrations. For each CD, the severe overlap in protonation step...

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Detalles Bibliográficos
Autores principales: Kalydi, Eszter, Malanga, Milo, Ujj, Dóra, Benkovics, Gábor, Szakács, Zoltán, Béni, Szabolcs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696085/
https://www.ncbi.nlm.nih.gov/pubmed/36430926
http://dx.doi.org/10.3390/ijms232214448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696085/
https://www.ncbi.nlm.nih.gov/pubmed/36430926
http://dx.doi.org/10.3390/ijms232214448

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