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Pancreatic Cancer Cell-Conditioned, Human-Derived Primary Myotubes Display Increased Leucine Turnover, Increased Lipid Accumulation, and Reduced Glucose Uptake

Metabolic alterations occurring in cancer cells have been seen to also occur in other tissues than cancerous tissue. For instance, cachexia, peripheral insulin resistance, or both are commonly seen in patients with cancer. We explored differences in substrate use in myotubes conditioned with the med...

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Detalles Bibliográficos
Autores principales: Krapf, Solveig A., Lund, Jenny, Saqib, Awais Ur Rehman, Bakke, Hege G., Rustan, Arild C., Thoresen, G. Hege, Kase, Eili T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696174/
https://www.ncbi.nlm.nih.gov/pubmed/36355178
http://dx.doi.org/10.3390/metabo12111095