Targeting Ultrasmall Gold Nanoparticles with cRGD Peptide Increases the Uptake and Efficacy of Cytotoxic Payload

Cyclic arginyl-glycyl-aspartic acid peptide (cRGD) peptides show a high affinity towards αVβ3 integrin, a receptor overexpressed in many cancers. We aimed to combine the versatility of ultrasmall gold nanoparticles (usGNP) with the target selectivity of cRGD peptide for the directed delivery of a cy...

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Detalles Bibliográficos
Autores principales: Perrins, Richard D., McCarthy, Lee-Anne, Robinson, Angela, Spry, Kelly L., Cognet, Valentin, Ferreira, Avelino, Porter, John, Garcίa, Cristina Espinosa, Rodriguez, Miguel Ángel, Lopez, Diana, Perera, Ibon, Conlon, Kelly, Barrientos, Africa, Coulter, Tom, Pace, Alessandro, Hale, Sarah J. M., Ferrari, Enrico, Bachrati, Csanad Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696180/
https://www.ncbi.nlm.nih.gov/pubmed/36432299
http://dx.doi.org/10.3390/nano12224013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696180/
https://www.ncbi.nlm.nih.gov/pubmed/36432299
http://dx.doi.org/10.3390/nano12224013

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