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Targeting Ultrasmall Gold Nanoparticles with cRGD Peptide Increases the Uptake and Efficacy of Cytotoxic Payload
Cyclic arginyl-glycyl-aspartic acid peptide (cRGD) peptides show a high affinity towards αVβ3 integrin, a receptor overexpressed in many cancers. We aimed to combine the versatility of ultrasmall gold nanoparticles (usGNP) with the target selectivity of cRGD peptide for the directed delivery of a cy...
Autores principales: | Perrins, Richard D., McCarthy, Lee-Anne, Robinson, Angela, Spry, Kelly L., Cognet, Valentin, Ferreira, Avelino, Porter, John, Garcίa, Cristina Espinosa, Rodriguez, Miguel Ángel, Lopez, Diana, Perera, Ibon, Conlon, Kelly, Barrientos, Africa, Coulter, Tom, Pace, Alessandro, Hale, Sarah J. M., Ferrari, Enrico, Bachrati, Csanad Z. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696180/ https://www.ncbi.nlm.nih.gov/pubmed/36432299 http://dx.doi.org/10.3390/nano12224013 |
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