The Translational Landscape Revealed the Sequential Treatment Containing ATRA plus PI3K/AKT Inhibitors as an Efficient Strategy for AML Therapy

The present study aimed to better understand the possibility of utilizing all-trans retinoic acids (ATRA) in acute myeloid leukemia (AML). We found that ATRA significantly suppressed global translation and protein synthesis in AML cells. The efficacy of ATRA in treating AML required its translationa...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Ke, Ou, Ziyao, Deng, Ge, Li, Shufang, Su, Jingjing, Xu, Yayun, Zhou, Renpeng, Hu, Wei, Chen, Feihu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696193/
https://www.ncbi.nlm.nih.gov/pubmed/36365147
http://dx.doi.org/10.3390/pharmaceutics14112329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696193/
https://www.ncbi.nlm.nih.gov/pubmed/36365147
http://dx.doi.org/10.3390/pharmaceutics14112329

Ejemplares similares