Involvement of Transporters in Intestinal Drug–Drug Interactions of Oral Targeted Anticancer Drugs Assessed by Changes in Drug Absorption Time

(1) Background: Oral targeted anticancer drugs are victims of presystemic pharmacokinetic drug–drug interactions (DDI). Identification of the nature of these DDIs, i.e., enzyme-based or/and transporter-based, is challenging, since most of these drugs are substrates of intestinal and/or hepatic cytoc...

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Detalles Bibliográficos
Autores principales: Malnoë, David, Fardel, Olivier, Le Corre, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696196/
https://www.ncbi.nlm.nih.gov/pubmed/36432682
http://dx.doi.org/10.3390/pharmaceutics14112493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696196/
https://www.ncbi.nlm.nih.gov/pubmed/36432682
http://dx.doi.org/10.3390/pharmaceutics14112493

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