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Prospects for the Development of Pink1 and Parkin Activators for the Treatment of Parkinson’s Disease

Impaired mitophagy is one of the hallmarks of the pathogenesis of Parkinson’s disease, which highlights the importance of the proper functioning of mitochondria, as well as the processes of mitochondrial dynamics for the functioning of dopaminergic neurons. At the same time, the main factors leading...

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Detalles Bibliográficos
Autores principales: Blagov, Alexander V., Goncharov, Andrey G., Babich, Olga O., Larina, Viktoriya V., Orekhov, Alexander N., Melnichenko, Alexandra A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696222/
https://www.ncbi.nlm.nih.gov/pubmed/36432705
http://dx.doi.org/10.3390/pharmaceutics14112514