Secondary Structure Characterization of Glucagon Products by Circular Dichroism and Nuclear Magnetic Resonance Spectroscopy

Glucagon, a 29-amino acid polypeptide hormone, is an essential therapeutic agent used in the emergency treatment of hypoglycemia. However, glucagon is inherently unstable in aqueous solution. While glucagon equilibrates between unordered and the secondary α-helix state in solution, it can quickly tr...

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Detalles Bibliográficos
Autores principales: Bao, Zhongli, Cheng, Ya-Chi, Wei, Justin Jun, Luo, Mary Ziping, Zhang, Jack Yongfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696263/
https://www.ncbi.nlm.nih.gov/pubmed/36431905
http://dx.doi.org/10.3390/molecules27227805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696263/
https://www.ncbi.nlm.nih.gov/pubmed/36431905
http://dx.doi.org/10.3390/molecules27227805

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