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Antiandrogenic Effects of a Polyphenol in Carex kobomugi through Inhibition of Androgen Synthetic Pathway and Downregulation of Androgen Receptor in Prostate Cancer Cell Lines

Prostate cancer (PC) represents the most common cancer disease in men. Since high levels of androgens increase the risk of PC, androgen deprivation therapy is the primary treatment; however this leads to castration-resistant PC (CRPC) with a poor prognosis. The progression to CRPC involves ectopic a...

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Detalles Bibliográficos
Autores principales: Kudo, Yudai, Endo, Satoshi, Tanio, Masatoshi, Saka, Tomofumi, Himura, Rin, Abe, Naohito, Takeda, Mitsumi, Yamaguchi, Eiji, Yoshino, Yuta, Arai, Yuki, Kashiwagi, Hirohito, Oyama, Masayoshi, Itoh, Akichika, Shiota, Masaki, Fujimoto, Naohiro, Ikari, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696374/
https://www.ncbi.nlm.nih.gov/pubmed/36430833
http://dx.doi.org/10.3390/ijms232214356