Cargando…
Antiandrogenic Effects of a Polyphenol in Carex kobomugi through Inhibition of Androgen Synthetic Pathway and Downregulation of Androgen Receptor in Prostate Cancer Cell Lines
Prostate cancer (PC) represents the most common cancer disease in men. Since high levels of androgens increase the risk of PC, androgen deprivation therapy is the primary treatment; however this leads to castration-resistant PC (CRPC) with a poor prognosis. The progression to CRPC involves ectopic a...
Autores principales: | Kudo, Yudai, Endo, Satoshi, Tanio, Masatoshi, Saka, Tomofumi, Himura, Rin, Abe, Naohito, Takeda, Mitsumi, Yamaguchi, Eiji, Yoshino, Yuta, Arai, Yuki, Kashiwagi, Hirohito, Oyama, Masayoshi, Itoh, Akichika, Shiota, Masaki, Fujimoto, Naohiro, Ikari, Akira |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696374/ https://www.ncbi.nlm.nih.gov/pubmed/36430833 http://dx.doi.org/10.3390/ijms232214356 |
Ejemplares similares
-
Androgens and environmental antiandrogens affect reproductive development and play behavior in the Sprague-Dawley rat.
por: Hotchkiss, A K, et al.
Publicado: (2002) -
Interlaboratory comparison of four in vitro assays for assessing androgenic and antiandrogenic activity of environmental chemicals.
por: Körner, Wolfgang, et al.
Publicado: (2004) -
Antiandrogens Act as Selective Androgen Receptor Modulators at the Proteome Level in Prostate Cancer Cells
por: Brooke, Greg N., et al.
Publicado: (2015) -
Efficacy of Alternative Antiandrogen Therapy for Prostate Cancer That Relapsed after Initial Maximum Androgen Blockade
por: Choi, Joon Il, et al.
Publicado: (2011) -
GREB1 amplifies androgen receptor output in human prostate cancer and contributes to antiandrogen resistance
por: Lee, Eugine, et al.
Publicado: (2019)