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The Role of Hidden Conformers in Determination of Conformational Preferences of Mefenamic Acid by NOESY Spectroscopy

Mefenamic acid has been used as a non-steroidal anti-inflammatory drug for a long time. However, its practical use is quite limited due to a number of side effects on the intestinal organs. Conformational polymorphism provides mefenamic acid with unique properties regarding possible modifications ob...

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Detalles Bibliográficos
Autores principales: Belov, Konstantin V., Batista de Carvalho, Luís A. E., Dyshin, Alexey A., Efimov, Sergey V., Khodov, Ilya A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696638/
https://www.ncbi.nlm.nih.gov/pubmed/36365095
http://dx.doi.org/10.3390/pharmaceutics14112276