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A Polymorphism in the TMPRSS2 Gene Increases the Risk of Death in Older Patients Hospitalized with COVID-19

Background: Transmembrane serine protease type 2 (TMPRSS2) and angiotensin-converting enzyme 2 (ACE2) are the main molecules involved in the entry of SARS-CoV-2 into host cells. Changes in TMPRSS2 expression levels caused by single nucleotide polymorphisms (SNPs) may contribute to the outcome of COV...

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Detalles Bibliográficos
Autores principales: de Andrade, Clara Caldeira, Silva, Ana Tércia Paulo, Vasconcelos, Luydson Richardson Silva, Oliveira, Pablo Rafael Silveira, de Souza, Carlos Dornels Freire, da Costa Armstrong, Anderson, do Carmo, Rodrigo Feliciano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696669/
https://www.ncbi.nlm.nih.gov/pubmed/36423166
http://dx.doi.org/10.3390/v14112557