Benzenesulfonamides Incorporating Hydantoin Moieties Effectively Inhibit Eukaryoticand Human Carbonic Anhydrases

A series of novel 1-(4-benzenesulfonamide)-3-alkyl/benzyl-hydantoin derivatives were synthesized and evaluated for the inhibition of eukaryotic and human carbonic anhydrases (CAs, EC 4.2.1.1). The prepared compounds were screened for their hCA inhibitory activities against three cytosolic isoforms a...

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Detalles Bibliográficos
Autores principales: Abdoli, Morteza, De Luca, Viviana, Capasso, Clemente, Supuran, Claudiu T., Žalubovskis, Raivis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696710/
https://www.ncbi.nlm.nih.gov/pubmed/36430592
http://dx.doi.org/10.3390/ijms232214115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696710/
https://www.ncbi.nlm.nih.gov/pubmed/36430592
http://dx.doi.org/10.3390/ijms232214115

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