Design, Synthesis and Pharmacological Evaluation of Novel C(2),C(3)-Quinoxaline Derivatives as Promising Anxiolytic Agents

A new series of quinoxaline derivatives, 2a–4b, were synthesized and their anxiolytic potential was evaluated in vivo using elevated plus maze (EPM), open field (OF) and light-dark box (LDB) techniques. According to the results of the EPM, four active compounds were found in 2a, 2b, 2c, 4b. Their an...

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Detalles Bibliográficos
Autores principales: Maltsev, Dmitriy V., Skripka, Maria O., Spasov, Alexander A., Vassiliev, Pavel M., Perfiliev, Maxim A., Divaeva, Lyudmila N., Zubenko, Alexander A., Morkovnik, Anatolii S., Klimenko, Alexander I., Miroshnikov, Mikhail V., Klochkov, Vladlen G., Ianalieva, Laura R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696749/
https://www.ncbi.nlm.nih.gov/pubmed/36430878
http://dx.doi.org/10.3390/ijms232214401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696749/
https://www.ncbi.nlm.nih.gov/pubmed/36430878
http://dx.doi.org/10.3390/ijms232214401

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