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Biological Significance of Dual Mutations A494D and E495K of the Genotype III Newcastle Disease Virus Hemagglutinin-Neuraminidase In Vitro and In Vivo

As a multifunctional protein, the hemagglutinin-neuraminidase (HN) protein of Newcastle disease virus (NDV) is involved in various biological functions. A velogenic genotype III NDV JS/7/05/Ch evolving from the mesogenic vaccine strain Mukteswar showed major amino acid (aa) mutations in the HN prote...

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Detalles Bibliográficos
Autores principales: Lu, Xiaolong, Zhan, Tiansong, Liu, Kaituo, Chen, Yu, Hu, Zenglei, Hu, Jiao, Gu, Min, Hu, Shunlin, Wang, Xiaoquan, Liu, Xiaowen, Liu, Xiufan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696791/
https://www.ncbi.nlm.nih.gov/pubmed/36366435
http://dx.doi.org/10.3390/v14112338