MLN4924 Treatment Diminishes Excessive Lipid Storage in High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease (NAFLD) by Stimulating Hepatic Mitochondrial Fatty Acid Oxidation and Lipid Metabolites

MLN4924 is a selective neddylation inhibitor that has shown great potential in treating several cancer and metabolic diseases, including obesity. However, it remains largely unknown whether MLN4924 has similar effect on non-alcoholic liver disease (NAFLD), which is closely associated with metabolic...

Descripción completa

Detalles Bibliográficos
Autores principales: Ge, Mengxiao, Huang, Linlin, Ma, Yinjun, Sun, Shuangyi, Wu, Lijun, Xu, Wei, Yang, Dongqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696831/
https://www.ncbi.nlm.nih.gov/pubmed/36432651
http://dx.doi.org/10.3390/pharmaceutics14112460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696831/
https://www.ncbi.nlm.nih.gov/pubmed/36432651
http://dx.doi.org/10.3390/pharmaceutics14112460

Ejemplares similares