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MLN4924 Treatment Diminishes Excessive Lipid Storage in High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease (NAFLD) by Stimulating Hepatic Mitochondrial Fatty Acid Oxidation and Lipid Metabolites

MLN4924 is a selective neddylation inhibitor that has shown great potential in treating several cancer and metabolic diseases, including obesity. However, it remains largely unknown whether MLN4924 has similar effect on non-alcoholic liver disease (NAFLD), which is closely associated with metabolic...

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Detalles Bibliográficos
Autores principales:	Ge, Mengxiao, Huang, Linlin, Ma, Yinjun, Sun, Shuangyi, Wu, Lijun, Xu, Wei, Yang, Dongqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696831/ https://www.ncbi.nlm.nih.gov/pubmed/36432651 http://dx.doi.org/10.3390/pharmaceutics14112460

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