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Application of AP-MALDI Imaging Mass Microscope for the Rapid Mapping of Imipramine, Chloroquine, and Their Metabolites in the Kidney and Brain of Wild-Type Mice

Mass spectrometry imaging (MSI) is well-known for the non-labeling visualization of analytes, including drugs and their metabolites in biological samples. In this study, we applied three different tools of MSI, desorption electrospray ionization (DESI)-MSI, matrix-assisted laser desorption ionizatio...

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Detalles Bibliográficos
Autores principales: Islam, Ariful, Sakamoto, Takumi, Zhai, Qing, Rahman, Md. Muedur, Mamun, Md. Al, Takahashi, Yutaka, Kahyo, Tomoaki, Setou, Mitsutoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696843/
https://www.ncbi.nlm.nih.gov/pubmed/36355486
http://dx.doi.org/10.3390/ph15111314