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The Novel AT2 Receptor Agonist β-Pro7-AngIII Exerts Cardiac and Renal Anti-Fibrotic and Anti-Inflammatory Effects in High Salt-Fed Mice

A high salt (HS) diet is associated with an increased risk for cardiovascular diseases (CVDs) and fibrosis is a key contributor to the organ dysfunction involved in CVDs. The activation of the renin angiotensin type 2 receptor (AT(2)R) has been considered as organ protective in many CVDs. However, t...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Yodgee, Jonathan, Del Borgo, Mark, Spizzo, Iresha, Nguyen, Levi, Aguilar, Marie-Isabel, Denton, Kate M., Samuel, Chrishan S., Widdop, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696912/
https://www.ncbi.nlm.nih.gov/pubmed/36430518
http://dx.doi.org/10.3390/ijms232214039