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Iridium-Catalyzed and pH-Dependent Reductions of Nitroalkenes to Ketones

A highly chemoselective conversion of α,β-disubstituted nitroalkenes to ketones is developed. An acid-compatible iridium catalyst serves as the key to the conversion. At a 2500 S/C ratio, nitroalkenes were readily converted to ketones in up to 72% isolated yields. A new mechanistic mode involving th...

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Detalles Bibliográficos
Autores principales: Wang, Tingting, Liu, Changmeng, Xu, Dong, Xu, Jiaxi, Yang, Zhanhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696932/
https://www.ncbi.nlm.nih.gov/pubmed/36431923
http://dx.doi.org/10.3390/molecules27227822