Synthesis of Glycolysis Inhibitor PFK15 and Its Synergistic Action with an Approved Multikinase Antiangiogenic Drug on Human Endothelial Cell Migration and Proliferation

Activated endothelial, immune, and cancer cells prefer glycolysis to obtain energy for their proliferation and migration. Therefore, the blocking of glycolysis can be a promising strategy against cancer and autoimmune disease progression. Inactivation of the glycolytic enzyme PFKFB3 (6-phosphofructo...

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Detalles Bibliográficos
Autores principales: Zlacká, Jana, Murár, Miroslav, Addová, Gabriela, Moravčík, Roman, Boháč, Andrej, Zeman, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697023/
https://www.ncbi.nlm.nih.gov/pubmed/36430773
http://dx.doi.org/10.3390/ijms232214295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697023/
https://www.ncbi.nlm.nih.gov/pubmed/36430773
http://dx.doi.org/10.3390/ijms232214295

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