Probing Pharmaceutical Strategies to Promote the Skin Delivery of Asiatic Acid from Hydrogels: Enhancement Effects of Organic Amine Counterions, Chemical Enhancers, and Microneedle Pretreatment

Asiatic acid (AA) is a pentacyclic triterpene isolated from Centella asiatica, holding great promise for treating a variety of skin disorders. However, the dermal application of AA is limited by its poor solubility and permeability. This study aimed to identify a hydrogel formulation for AA and impr...

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Detalles Bibliográficos
Autores principales: Li, Mingming, Wang, Qiuyue, Chen, Naiying, Yao, Sicheng, Sun, Xinxing, Quan, Peng, Chen, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697078/
https://www.ncbi.nlm.nih.gov/pubmed/36432722
http://dx.doi.org/10.3390/pharmaceutics14112532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697078/
https://www.ncbi.nlm.nih.gov/pubmed/36432722
http://dx.doi.org/10.3390/pharmaceutics14112532

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