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Analysis of Compositional Bias in a Commercial Phage Display Peptide Library by Next-Generation Sequencing

The principal presumption of phage display biopanning is that the naïve library contains an unbiased repertoire of peptides, and thus, the enriched variants derive from the affinity selection of an entirely random peptide pool. In the current study, we utilized deep sequencing to characterize the wi...

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Detalles Bibliográficos
Autores principales: Sloth, Ane Beth, Bakhshinejad, Babak, Jensen, Malte, Stavnsbjerg, Camilla, Liisberg, Mikkel Baldtzer, Rossing, Maria, Kjaer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697088/
https://www.ncbi.nlm.nih.gov/pubmed/36366500
http://dx.doi.org/10.3390/v14112402