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Analysis of Compositional Bias in a Commercial Phage Display Peptide Library by Next-Generation Sequencing
The principal presumption of phage display biopanning is that the naïve library contains an unbiased repertoire of peptides, and thus, the enriched variants derive from the affinity selection of an entirely random peptide pool. In the current study, we utilized deep sequencing to characterize the wi...
Autores principales: | Sloth, Ane Beth, Bakhshinejad, Babak, Jensen, Malte, Stavnsbjerg, Camilla, Liisberg, Mikkel Baldtzer, Rossing, Maria, Kjaer, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697088/ https://www.ncbi.nlm.nih.gov/pubmed/36366500 http://dx.doi.org/10.3390/v14112402 |
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