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Green Synthesis of Spiro Compounds with Potential Anticancer Activity through Knoevenagel/Michael/Cyclization Multicomponent Domino Reactions Organocatalyzed by Ionic Liquid and Microwave-Assisted

In this work a microwave-assisted Knoevenagel/Michael/cyclization multicomponent domino methodology, using ethanol as solvent and the ionic liquid 1-methylimidazolium chloride as catalyst was developed for the synthesis of spiro compounds. The reaction conditions considered ideal were determined fro...

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Detalles Bibliográficos
Autores principales: Westphal, Regina, Venturini Filho, Eclair, Loureiro, Laiza Bruzadelle, Tormena, Cláudio Francisco, Pessoa, Claudia, Guimarães, Celina de Jesus, Manso, Mariana Palmeira, Fiorot, Rodolfo Goetze, Campos, Vinicius Rangel, Resende, Jackson Antônio Lamounier Camargos, Medici, Fabrizio, Greco, Sandro José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697156/
https://www.ncbi.nlm.nih.gov/pubmed/36432151
http://dx.doi.org/10.3390/molecules27228051