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Simultaneous Inhibition of Histone Deacetylases and RNA Synthesis Enables Totipotency Reprogramming in Pig SCNT Embryos

Combining somatic cell nuclear transfer (SCNT) with genome editing technologies has emerged as a powerful platform for the creation of unique swine lineages for agricultural and biomedical applications. However, successful application of this research platform is still hampered by the low efficiency...

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Detalles Bibliográficos
Autores principales: de Macedo, Mariana Priotto, Glanzner, Werner Giehl, Gutierrez, Karina, Currin, Luke, Guay, Vanessa, Carrillo Herrera, Maria Elena, da Silva, Zigomar, Baldassarre, Hernan, McGraw, Serge, Bordignon, Vilceu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697165/
https://www.ncbi.nlm.nih.gov/pubmed/36430635
http://dx.doi.org/10.3390/ijms232214142