5-HT(1A) Receptor Agonist Treatment Partially Ameliorates Rett Syndrome Phenotypes in mecp2-Null Mice by Rescuing Impairment of Neuron Transmission and the CREB/BDNF Signaling Pathway

Rett syndrome (RTT) is an X-linked neurodevelopmental disorder caused by mutations in the gene that encodes methyl CpG-binding protein 2 (MECP2) and is characterized by the loss of acquired motor and language skills, stereotypic movements, respiratory abnormalities and autistic features. There has b...

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Detalles Bibliográficos
Autores principales: Dai, Hongmei, Kitami, Yoshikazu, Goto, Yu-ichi, Itoh, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697184/
https://www.ncbi.nlm.nih.gov/pubmed/36430502
http://dx.doi.org/10.3390/ijms232214025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697184/
https://www.ncbi.nlm.nih.gov/pubmed/36430502
http://dx.doi.org/10.3390/ijms232214025

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