Carbonic Anhydrase Inhibition Activities of Schiff’s Bases Based on Quinazoline-Linked Benzenesulfonamide

Human carbonic anhydrase (CA, EC 4.2.1.1) (hCA) isoforms I, II, IX, and XII were investigated for their inhibitory activity with a series of new Schiff’s bases based on quinazoline scaffold 4–27. The hCA I isoform was efficiently inhibited by Schiff’s bases 4–6, 10–19, 22–27 and had an inhibition co...

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Detalles Bibliográficos
Autores principales: El-Azab, Adel S., Abdel-Aziz, Alaa A.-M., Ghabbour, Hazem A., Bua, Silvia, Nocentini, Alessio, Alkahtani, Hamad M., Alsaif, Nawaf A., Al-Agamy, Mohamed H. M., Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697198/
https://www.ncbi.nlm.nih.gov/pubmed/36431826
http://dx.doi.org/10.3390/molecules27227703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697198/
https://www.ncbi.nlm.nih.gov/pubmed/36431826
http://dx.doi.org/10.3390/molecules27227703

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