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Carbonic Anhydrase Inhibition Activities of Schiff’s Bases Based on Quinazoline-Linked Benzenesulfonamide

Human carbonic anhydrase (CA, EC 4.2.1.1) (hCA) isoforms I, II, IX, and XII were investigated for their inhibitory activity with a series of new Schiff’s bases based on quinazoline scaffold 4–27. The hCA I isoform was efficiently inhibited by Schiff’s bases 4–6, 10–19, 22–27 and had an inhibition co...

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Detalles Bibliográficos
Autores principales:	El-Azab, Adel S., Abdel-Aziz, Alaa A.-M., Ghabbour, Hazem A., Bua, Silvia, Nocentini, Alessio, Alkahtani, Hamad M., Alsaif, Nawaf A., Al-Agamy, Mohamed H. M., Supuran, Claudiu T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697198/ https://www.ncbi.nlm.nih.gov/pubmed/36431826 http://dx.doi.org/10.3390/molecules27227703

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