Enhancing Anti-G Antibody Induction by a Live Single-Cycle Prefusion F—Expressing RSV Vaccine Improves In Vitro and In Vivo Efficacy

The human respiratory syncytial virus (RSV) is a major cause of severe respiratory tract disease, and a vaccine is not available. We previously reported a novel live vaccine expressing prefusion-stabilized fusion protein (preF) in place of the native F protein (RSV-preF(ΔCT)). As preF is non-functio...

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Detalles Bibliográficos
Autores principales: Lamichhane, Pramila, Terhüja, Megolhubino, Snider, Timothy A., Oomens, Antonius G. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697216/
https://www.ncbi.nlm.nih.gov/pubmed/36366572
http://dx.doi.org/10.3390/v14112474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697216/
https://www.ncbi.nlm.nih.gov/pubmed/36366572
http://dx.doi.org/10.3390/v14112474

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